Untitled Document
By Dr Barry Durrant-Peatfield MBBS LRCP MRCS Medical Advisor to
Thyroid UK
There is a daunting amount of research studies showing that the widely acclaimed
benefits on fluoride dental health are more imagined than real. My main concern
however, is the effect of sustained fluoride intake on general health. Again,
there is a huge body of research literature on this subject, freely available
and in the public domain.
But this body of work was not considered by the York Review when their remit
was changed from "Studies of the effects of fluoride on health" to
"Studies on the effects of fluoridated water on health." It is clearly
evident that it was not considered by the BMA (Britsh Medical Association),
British Dental Association (BDA), BFS (British Fluoridation Society) and FPHM,
(Faculty for Public Health and Medicine) since they all insist, as in the briefing
paper to Members of Parliament - that fluoridation is safe and non-injurious
to health.
This is a public disgrace, I will now show by reviewing the damaging effects
of fluoridation, with special reference to thyroid illness.
It has been known since the latter part of the 19th century that certain communities,
notably in Argentina, India and Turkey were chronically ill, with premature
ageing, arthritis, mental retardation, and infertility; and high levels of natural
fluorides in the water were responsible. Not only was it clear that the fluoride
was having a general effect on the health of the community, but in the early
1920s Goldemberg, working in Argentina showed that fluoride was displacing iodine;
thus compounding the damage and rendering the community also hypothyroid from
iodine deficiency.
Highly Damaging To The Thyroid Gland
This was the basis of the research in the 1930s of May, Litzka, Gorlitzer von
Mundy, who used fluoride preparations to treat over-active thyroid illness.
Their patients either drank fluoridated water, swallowed fluoride pills or were
bathed in fluoridated bath water; and their thyroid function was as a result,
greatly depressed. The use in 1937 of fluorotyrosine for this purpose showed
how effective this treatment was; but the effectiveness was difficult to predict
and many patients suffered total thyroid loss. So it was given a new role and
received a new name, Pardinon. It was marketed not for over-active thyroid disease
but as a pesticide. (Note the manufacturer of fluorotyrosine was IG Farben who
also made sarin, a gas used in World War II).
This bit of history illustrates the fact that fluorides are dangerous in general
and in particular highly damaging to the thyroid gland, a matter to which I
shall return shortly. While it is unlikely that it will be disputed that fluorides
are toxic - let us be reminded that they are Schedule 2 Poisons under the Poisons
Act 1972, the matter in dispute is the level of toxicity attributable to given
amounts; in today's context the degree of damage caused by given concentrations
in the water supply. While admitting its toxicity, proponents rely on the fact
that it is diluted and therefore, it is claimed, unlikely to have deleterious
effects.
They Could Not Be More Mistaken
It seems to me that we must be aware of how fluoride does its damage. It is
an enzyme poison. Enzymes are complex protein compounds that vastly speed up
biological chemical reactions while themselves remaining unchanged. As we speak,
there occurs in all of us a vast multitude of these reactions to maintain life
and produce the energy to sustain it. The chains of amino acids that make up
these complex proteins are linked by simple compounds called amides; and it
is with these that fluorine molecules react, splitting and distorting them,
thus damaging the enzymes and their activity. Let it be said at once, this effect
can occur at extraordinary low concentrations; even lower than the one part
per million which is the dilution proposed for fluoridation in our water supply.
The Body Can Only Eliminate Half
Moreover, fluorides are cumulative and build up steadily with ingestion of fluoride
from all sources, which include not just water but the air we breathe and the
food we eat. The use of fluoride toothpaste in dental hygiene and the coating
of teeth are further sources of substantial levels of fluoride intake. The body
can only eliminate half of the total intake, which means that the older you
are the more fluoride will have accumulated in your body. Inevitably this means
the ageing population is particularly targeted. And even worse for the very
young there is a major element of risk in baby formula made with fluoridated
water. The extreme sensitivity of the very young to fluoride toxicity makes
this unacceptable. Since there are so many sources of fluoride in our everyday
living, it will prove impossible to maintain an average level of 1ppm as is
suggested.
What Is The Result Of These Toxic Effects?
First the immune system. The distortion of protein structure causes the immune
proteins to fail to recognise body proteins, and so instigate an attack on them,
which is Autoimmune Disease. Autoimmune diseases constitute a body of disease
processes troubling many thousands of people: Rheumatoid Arthritis, Systemic
Lupus Erythematosis, Asthma and Systemic Sclerosis are examples; but in my particular
context today, thyroid antibodies will be produced which will cause Thyroiditis
resulting in the common hypothyroid disease, Hashimoto's Disease and the hyperthyroidism
of Graves' Disease.
Musculo Skeletal damage results further from the enzyme toxic effect; the collagen
tissue of which muscles, tendons, ligaments and bones are made, is damaged.
Rheumatoid illness, osteoporosis and deformation of bones inevitably follow.
This toxic effect extends to the ameloblasts making tooth enamel, which is consequently
weakened and then made brittle; and its visible appearance is, of course, dental
fluorosis.
The enzyme poison effect extends to our genes; DNA cannot repair itself, and
chromosomes are damaged. Work at the University of Missouri showed genital damage,
targeting ovaries and testes. Also affected is inter uterine growth and development
of the foetus, especially the nervous system. Increased incidence of Down's
Syndrome has been documented.
Fluorides are mutagenic. That is, they can cause the uncontrolled proliferation
of cells we call cancer. This applies to cancer anywhere in the body; but bones
are particularly picked out. The incidence of osteosarcoma in a study reporting
in 1991 showed an unbelievable 50% increase. A report in 1955 in the New England
Journal of Medicine showed a 400% increase in cancer of the thyroid in San Francisco
during the period their water was fluoridated.
My Particular Concern Is The Effect Of Fluorides On The Thyroid Gland
Perhaps I may remind you about thyroid disease. The thyroid gland produces hormones
which control our metabolism - the rate at which we burn our fuel. Deficiency
is relatively common, much more than is generally accepted by many medical authorities:
a figure of 1:4 or 1:3 by mid life is more likely. The illness is insidious
in its onset and progression. People become tired, cold, overweight, depressed,
constipated; they suffer arthritis, hair loss, infertility, atherosclerosis
and chronic illness. Sadly, it is poorly diagnosed and poorly managed by very
many doctors in this country.
What concerns me so deeply is that in concentrations as low as 1ppm, fluorides
damage the thyroid system on 4 levels.
1. The enzyme manufacture of thyroid hormones within the thyroid gland itself.
The process by which iodine is attached to the amino acid tyrosine and converted
to the two significant thyroid hormones, thyroxine (T4) and liothyronine (T3),
is slowed.
2. The stimulation of certain G proteins from the toxic effect of fluoride (whose
function is to govern uptake of substances into each of the cells of the body),
has the effect of switching off the uptake into the cell of the active thyroid
hormone.
3. The thyroid control mechanism is compromised. The thyroid stimulating hormone
output from the pituitary gland is inhibited by fluoride, thus reducing thyroid
output of thyroid hormones.
4. Fluoride competes for the receptor sites on the thyroid gland which respond
to the thyroid stimulating hormone; so that less of this hormone reaches the
thyroid gland and so less thyroid hormone is manufactured. These damaging effects,
all of which occur with small concentrations of fluoride, have obvious and easily
identifiable effects on thyroid status. The running down of thyroid hormone
means a slow slide into hypothyroidism. Already the incidence of hypothyroidism
is increasing as a result of other environmental toxins and pollutions together
with wide spread nutritional deficiencies.
141 Million Europeans Are At Risk
One further factor should give us deep anxiety. Professor Hume of Dundee, in
his paper given earlier this year to the Novartis Foundation, pointed out that
iodine deficiency is growing worldwide. There are 141 million Europeans are
at risk; only 5 European countries are iodine sufficient. UK now falls into
the marginal and focal category. Professor Hume recently produced figures to
show that 40% of pregnant women in the Tayside region of Scotland were deficient
by at least half of the iodine required for a normal pregnancy. A relatively
high level of missing, decayed, filled teeth was noted in this non-fluoridated
area, suggesting that the iodine deficiency was causing early hypothyroidism
which interferes with the health of teeth. Dare one speculate on the result
of now fluoridating the water?...
Displaces Iodine In The Body
Do you think it should be marketed?
Fluoridation of the nation's water supply will do little for our dental health;
but will have catastrophic effects on our general health. We cannot, must not,
dare not, subject our nation to this appalling risk....
References
L Goldemberg - La Semana Med 28:628 (1921) - cited in Wilson RH, DeEds F -"The
Synergistic Action Of Thyroid On Fluoride Toxicity" Endocrinology 26:851
(1940).
G Litzka - "Die experimentellen Grundlagen der Behandlung des Morbus Basedow
und der Hyperthyreose mittels Fluortyrosin" Med Wochenschr 63:1037-1040
(1937) (discusses the basis of the use of fluorides in anti-thyroid medication,
documents activity on liver, inhibition of glycolysis, etc.).
W May - "Behandlung der Hypothyreosen einschlieblich des schweren genuinen
Morbus Basedow mit Fluor" Klin Wochenschr 16: 562 - 564 (1937).
Sarin: (GB: isopropyl methylphosono-fluoridate) is a colorless, odorless volatile
liquid, soluble in water, first synthesized at IG Farben in 1938. It kills mainly
through inhalation.
Cyclosarin (GF) and Thiosarin are variants. Pennsylvania Department of Health
http://www.dsf.health.state.pa.us/health/cwp/view.asp?a=171&q=233740
Sarin: (GB: CH3-P(=O)(-F)(-OCH(CH3)2)
Source: A FOA Briefing Book on Chemical Weapons
Gerhard Schrader, a chemist at IG Farben, was given the task of developing a
pesticide. Two years later a phosphorus compound with extremely high toxicity
was produced for the first time. IG Farben: "...the board of American IG
Farben had three directors from the Federal Reserve Bank of New York, the most
influential of the various Federal Reserve Banks. American IG Farben. also had
interlocks with Standard Oil of New Jersey, Ford Motor Company, Bank of Manhattan
(later to become the Chase Manhattan Bank), and AEG. (German General Electric)
Source: Moody's Manual of Investments; 1930, page 2149."
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